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Tricyclic Antidepressants (TCAs)

Treatments Related to Tricyclic Antidepressants (TCAs)

Because of the side effects associated with tricyclic antidepressants, psychiatrist and other physicians today often prescribe other, newer medications to treat depression. The most common are called selective serotonin reuptake inhibitors (SSRIs), which include fluoxetine (brand name: Prozac), citalopram (Celexa), sertraline (Zoloft), paroxetine (Paxil) and escitalopram (Lexapro). Another group of common prescribed antidepressants are the SNRIs, or serotonin and norepinephrine reuptake inhibitors, which include venlafaxine (Effexor) and duloxetine (Cymbalta); in addition, there is bupropion (Wellbutrin), a unique drug that works on the neurotransmitter dopamine.

These drugs tend to not cause as many side effects as do tricyclic antidepressants, though they may have some side effects, especially during the first few days of use, including headache, nausea, sleepiness, agitation and sexual problems. 

Locations for Tricyclic Antidepressants (TCAs)