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Squamous Cell Carcinoma (SCC)

Causes of Squamous Cell Carcinoma (SCC)

What causes squamous cell carcinoma? Most common skin cancer cases are found in white and fair-skinned people, where these types of skin complexion are highly susceptible to natural and artificial UV radiation. The causes of SCC are also associated with old age, rare skin conditions, and smoking. Squamous cell carcinoma causes visible nodules and/or red,scaly patches of skin to form on sun-exposed regions. As shown in reported cases, overexposure to the sun's UVA and UVB rays is the leading cause of squamous cell carcinoma (SCC). Find more information here.
The risk factors for squamous cell carcinoma include the following:
  • Older age
  • Male gender
  • Human papilloma virus (HPV) infection
  • Smoking
  • History of skin cancer
  • Immunosuppression (patients who have had previous organ transplants)
  • Treatment of psoriasis
  • Long-term skin inflammation or injury
  • Radiation exposure
  • Exposure to certain chemicals
  • Excessive exposure to UV radiation (sunlight or tanning beds)
  • Xeroderma pigmentosum (XP, a rare inherited condition)   

Locations for Squamous Cell Carcinoma (SCC)