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Pentosan Polysulfate

Related Treatments for Pentosan Polysulfate

If you are suffering from interstitial cystitis, pentosan polysulfate is not your only option. Other treatment options include:

  • Narcotic painkillers
  • Tricyclic antidepressants to relieve pain and urinary frequency
  • Vistaril, an antihistamine that causes sedation and helps reduce urinary frequency
  • Transcutaneous electrical nerve stimulation (TENS), in which mild electric pulses are sent into the body for up to a few hours two or more times a day, either through wires placed on the lower back or special devices inserted into the vagina (for women) or rectum (for men)
  • Bladder distention, a procedure to improve bladder capacity and interfere with pain signals transmitted by nerve cells in the bladder by over-filling the bladder with fluid while the patient is under general anesthesia
  • Bladder instillation, in which the bladder is filled with a solution that is held for a period of time ranging for a few seconds to 15 minutes, after which the fluid is drained through a catheter
  • Bladder training, in which the patient urinates at designated times, then uses relaxation techniques to keep to the schedule, graduating trying to lengthen the time between scheduled urinations
  • Physical therapy and biofeedback, which has been shown to help relieve muscle spasms on the pelvic floor

If those treatments don’t work, surgery may be an option. Surgical options include cytoscopic manipulation of the bladder, bladder removal (called a cystectomy), bladder augmentation (to accommodate more urine), as well as two procedures, fulguration and resection, for people with bladder ulcers. 

Locations for Pentosan Polysulfate