Screening for omphaloceles can begin with prenatal ultrasounds in the second or third trimester of pregnancy. A fetal echocardiogram may also be used to look for heart abnormalities. Omphaloceles may also be detected by abnormal blood or serum results.
In some cases, however, an omphalocele will not be noticed until the baby is born. Then, it will be noticed during a physical exam; x-rays may also be performed to look for abnormalities of other organs or body parts.