Generally speaking, doctors will recommended treatments for the most cancerous type of cell found in a mixed glioma tumor. So, for instance, for a tumor made up of a low-grade oligodendroglioma and a high-grade anaplastic astrocytoma, treatment options would be focused on the anaplastic astrocytoma.
Surgery is the most common form of treatment for mixed gliomas. The surgeon will attempt to remove as much of the tumor as possible, as well as to relieve the pressure on the brain caused by the tumor. Radiation therapy and chemotherapy usually follow surgery in an effort to kill any remaining cancer cells. In addition, doctors will continue to monitor the brain to see if the glioma returns—and if it does, another surgical procedure may be required.