Because cystic fibrosis is a genetic disease, it is passed along from parents to child, so there is no guarantee of preventing your child from being born with the disease. Through DNA testing, you can, however, ensure that you or the person with whom you are procreating is not a carrier of the disease. However, this gene is very large and complex. Not all genetic mutations of cystic fibrosis have been discovered, and it is possible that you or your partner could be a carrier even though no genetic mutations were found in the testing.
About 80 percent of the time, a child born with cystic fibrosis will have no family history of the disease, as both parents are healthy. The disease only manifests when both parents are carriers, and even then there is only a 25 percent chance that the child will have cystic fibrosis.
The risk of developing a sporadic mutation in the cystic fibrosis gene (in cases where there is no family history of cystic fibrosis) varies depending on your race. Caucasians, for instance, have a one in 29 chance of a gene mutation and a one in 2,500 to 3,500 chance of having a child with the condition, whereas Asians only have a one in 90 chance of the genetic mutation and a one in 100,000 chance of having a child with cystic fibrosis.